Bioengineered Artificial Skin Market

Global Bioengineered Artificial Skin Market is valued at US$ 3.14 Billion in 2022 and it is expected to reach US$ 11.87 Billion by 2029 with a CAGR of 20.9% over the forecast period.

Global Bioengineered Artificial Skin Market: Global Size, Trends, Competitive, and Historical & Forecast Analysis, 2023-2029- The market will expand due to the increasing prevalence of chronic wounds and burns, growing geriatric population, and rising demand for aesthetic procedures.

Scope of Global Bioengineered Artificial Skin Market Report-

Bioengineered artificial skin refers to a synthetic substitute for human skin that is created using bioengineering techniques. It is designed to mimic the structure and functions of natural skin, providing a potential solution for patients with severe burns, chronic wounds, or other skin injuries. This advanced technology has a fascinating history that traces back to the early 1980s when scientists began exploring tissue engineering and regenerative medicine approaches.

The development of bioengineered artificial skin has been a result of continuous research and innovation in the field of biomedical engineering. The first breakthrough came with the creation of a two-layered skin construct called "Epicel," which was approved by the FDA in 1988 for the treatment of burn injuries. Since then, significant progress has been made, leading to the development of more complex and sophisticated bioengineered skin substitutes.

The applications of bioengineered artificial skin are diverse and far-reaching. It is primarily used in the medical field for the treatment of burn victims, diabetic ulcers, chronic wounds, and other complex skin injuries. By providing a temporary or permanent protective barrier, bioengineered artificial skin promotes wound healing, prevents infection, and reduces scarring. Additionally, it serves as a valuable tool for drug testing, cosmetic product development, and academic research related to skin biology.

The end-users of bioengineered artificial skin include hospitals, burn centers, specialized wound care clinics, and research institutions. Surgeons and wound care specialists are the primary users who incorporate bioengineered skin substitutes into their treatment protocols. These end users rely on the efficacy, safety, and quality of bioengineered artificial skin to improve patient outcomes and enhance the healing process.

Covid-19 Impact on the Global Bioengineered Artificial Skin Market:

The Covid-19 pandemic has had a significant impact on the bioengineered artificial skin market. While the demand for bioengineered artificial skin remains essential for the treatment of burn injuries and chronic wounds, the market has experienced certain challenges and changes. One of the primary impacts of the pandemic has been disruptions in the supply chain. Manufacturing facilities and distribution networks have faced constraints due to lockdowns, travel restrictions, and workforce shortages. These disruptions have led to delays in production and supply of bioengineered artificial skin, affecting the availability of these products for healthcare providers and patients.

Additionally, the focus of healthcare systems and resources has shifted towards managing the Covid-19 crisis, leading to a temporary reduction in elective procedures and non-essential treatments. As a result, the demand for bioengineered artificial skin in certain healthcare settings may have been lower during the pandemic.

However, it is important to note that the need for bioengineered artificial skin in the treatment of burn injuries and chronic wounds remains constant. As the pandemic subsides and healthcare systems stabilize, the demand for these products is expected to rebound. The market is likely to witness a resurgence as the backlog of delayed procedures is addressed and healthcare services return to normalcy.

Moreover, the Covid-19 pandemic has also highlighted the importance of advanced wound care and the need for innovative solutions to address complex skin injuries. This recognition may further drive research, development, and investment in the bioengineered artificial skin market in the post-pandemic period.

Key Players of Global Bioengineered Artificial Skin Market Report-

The bioengineered artificial skin market is driven by several key players, including.

• Organogenesis Holdings Inc.
• Smith & Nephew plc
• Integra Lifesciences Holdings Corporation
• Stratatech Corporation
• Tissue Regenix Group plc
• Avita Medical Ltd.
• PolarityTE Inc.
• Zimmer Biomet Holdings Inc.
• Surtex Instruments Limited
• Medline Industries Inc.
• Molnlycke Health Care AB
• Mylan N.V.
• Anika Therapeutics Inc.
• Intercytex Ltd. (formerly known as Avocet Medical Inc.)
• Kerecis hf.
• PolyNovo Limited
• Acelity L.P. Inc.
• RenovaCare Inc.
• Johnson & Johnson
• 3M Healthcare
• and others.

Global Bioengineered Artificial Skin Market Segmentation:-

By Product Type:

• Bilayered Bioengineered Artificial Skin
• Trilayered Bioengineered Artificial Skin
• Others

By Application:

• Chronic Wounds
• Burns
• Traumatic Wounds
• Diabetic Foot Ulcers
• Surgical Wounds

By End-User:

• Hospitals
• Specialty Wound Care Centers
• Ambulatory Surgical Centers
• Research Institutes

By Regional & Country Level:

• North America
  • US.
  • Canada
• Europe
  • UK.
  • France
  • Germany
  • Italy
• Asia Pacific
  • China
  • Japan
  • India
  • Southeast Asia
• Latin America
  • Brazil
  • Mexico
• Middle East and Africa
  • GCC
  • Africa
  • Rest of Middle East and Africa

Revenue Generation Model:

The revenue generation model for the bioengineered artificial skin market primarily relies on the sale of bioengineered skin substitutes to medical institutions. The manufacturers of bioengineered artificial skin generate revenue through direct sales to hospitals, clinics, and research institutions. Pricing models may vary depending on factors such as product features, manufacturing techniques, and market competition. Additionally, collaborations with pharmaceutical companies for drug testing purposes can also contribute to revenue generation.

Supply Chain Model:

The supply chain model for bioengineered artificial skin involves multiple stages. It begins with research and development in academic institutions and private laboratories, where scientists work on improving the design and functionality of bioengineered skin substitutes. Once a promising product is developed, it moves to the manufacturing stage, where specialized biotech companies scale up production. The manufactured bioengineered artificial skin is then distributed to medical institutions and research facilities through a network of distributors and supply chain partners.

Value Chain Model:

The value chain model for the bioengineered artificial skin market encompasses the entire process from research and development to end-user application. It includes various stakeholders such as researchers, engineers, manufacturers, distributors, healthcare providers, and patients. Each stage of the value chain adds value to the final product, ensuring its quality, efficacy, and accessibility. Collaboration among these stakeholders is crucial to drive innovation, improve manufacturing processes, and ensure the widespread adoption of bioengineered artificial skin for medical and research purposes.

Market Drivers:

Increasing prevalence of chronic wounds and burns: Chronic wounds, such as pressure ulcers, diabetic foot ulcers, and venous leg ulcers, affect a large population globally. These wounds can be challenging to heal and often require advanced wound care solutions like bioengineered artificial skin to promote healing and prevent complications.

For example; the annual incidence of diabetic foot ulcer worldwide is between 9.1 to 26.1 million. Around 15 to 25% of patients with diabetes mellitus will develop a diabetic foot ulcer during their lifetime. 

Similarly, burns are a common type of injury that can result in severe tissue damage and long-term complications. The growing incidence of burns, whether due to accidents, occupational hazards, or other causes, creates a substantial demand for effective wound healing solutions like bioengineered artificial skin. According to World Health Organization, approximately 180,000 deaths occur each year due to burns worldwide.

Growing geriatric population: The growing geriatric population is driven by several factors that contribute to increased life expectancy and declining fertility rates. Firstly, advancements in healthcare have led to improved disease management, prevention, and access to medical treatments, resulting in longer lifespans. Additionally, lifestyle changes, including healthier habits and increased awareness of preventive care, have contributed to better overall health and longevity.

Moreover, socioeconomic factors such as improved living standards, higher education levels, and better socioeconomic support systems have positively influenced the aging population. Lastly, declining fertility rates in many countries have shifted the population pyramid, leading to a larger proportion of older adults. Collectively, these drivers have led to the significant growth of the geriatric population worldwide.

The number of persons aged 65 years or older worldwide is expected to double over the next three decades, according to a new report by the United Nations (UN). The elderly population will reach 1.6 billion in 2050, accounting for more than 16 per cent of the global population.

Market Restraints:

The high cost of bioengineered artificial skin products poses a significant restraint in the market. The complex and intricate manufacturing processes involved in creating these advanced medical products, coupled with the use of specialized materials and technologies, contribute to their high cost. This pricing barrier can limit the accessibility of bioengineered artificial skin, particularly in resource-constrained healthcare systems and for patients without adequate insurance coverage.

Additionally, the high cost may deter healthcare providers from adopting these products as a standard treatment option, especially in cases where alternative, less expensive wound care options are available. Addressing the cost challenge is crucial to ensure broader availability and affordability of bioengineered artificial skin, enabling better patient outcomes.

Market Opportunities:

Increasing demand for regenerative medicine: The growing focus on regenerative medicine presents a significant opportunity for bioengineered artificial skin. The ability of these products to promote tissue regeneration and wound healing aligns with the broader trend towards regenerative therapies.

Advancements in 3D bioprinting technology: The rapid development of 3D bioprinting technology holds great promise for bioengineered artificial skin. This technology enables precise and customizable fabrication of complex skin structures, enhancing the functionality and efficacy of these products.

Market Trend Analysis:

Product and Technology Development Trends:

Integration of bioactive molecules: Researchers are exploring the incorporation of bioactive molecules, such as growth factors and cytokines, into bioengineered artificial skin to enhance wound healing, reduce inflammation, and promote tissue regeneration.

Development of composite scaffolds: Composite scaffolds combining different materials and structures are being investigated to mimic the complex properties of natural skin more effectively. This trend aims to improve the functionality and performance of bioengineered artificial skin products.

Customer Trends:

Shift towards minimally invasive treatments: Patients and healthcare providers are increasingly seeking minimally invasive treatment options, including bioengineered artificial skin, for wound healing. These products offer non-surgical and less painful alternatives compared to traditional skin grafting procedures.

Demand for natural-looking outcomes: Patients desire bioengineered artificial skin that provides not only functional wound healing but also natural-looking cosmetic outcomes. The focus is on products that can reduce scarring, improve skin texture, and enhance aesthetic appearance.

Market Competition Nature:

The bioengineered artificial skin market is highly competitive, with several key players vying for market share and driving innovation in the field. These companies employ various strategies to gain a competitive edge, including product development, collaborations, acquisitions, and market expansion. Here are examples of past strategies employed by companies in the market:

Product Development: Companies have focused on developing advanced bioengineered artificial skin products with enhanced properties, such as improved integration with host tissues, better wound healing outcomes, and customization options. For example, Organogenesis Holdings Inc. launched Apligraf®, a bioengineered living cell-based product for the treatment of chronic wounds.

Collaborations and Partnerships: Collaboration with research institutions, universities, and other industry players has been a strategy to foster innovation and leverage complementary expertise. Smith & Nephew, a prominent player in the market, partnered with researchers at Swansea University to develop a new bioengineered skin product.

Acquisitions and Mergers: Companies have pursued strategic acquisitions to expand their product portfolios and strengthen their market position. For instance, Integra Lifesciences Holdings Corporation acquired Derma Sciences, a leading manufacturer of advanced wound care products, including bioengineered skin substitutes.

Future Strategies in the Global Bioengineered Artificial Skin Market:

Market Expansion: Companies are likely to focus on expanding their market presence by entering new geographical regions with high unmet needs for advanced wound care solutions. This could involve establishing partnerships, distribution agreements, or direct market entry.

Focus on Clinical Evidence: Generating robust clinical evidence through well-designed studies and trials will be crucial for demonstrating the efficacy and safety of bioengineered artificial skin products. Companies may invest in clinical research and evidence generation to support market adoption and reimbursement.

Patient-Centric Approach: Future strategies may involve a patient-centric approach, addressing patient needs and preferences through user-friendly product designs, improved cosmetic outcomes, and patient education initiatives.

Geography Analysis:

North America is One of the Significant Markets for Bioengineered Artificial Skin, Characterized by Advanced Healthcare Systems:

In North America, particularly the United States, the market is driven by several factors. Firstly, the region has a substantial prevalence of chronic wounds and burns, stemming from lifestyle factors, an aging population, and the presence of advanced healthcare facilities. This drives the demand for bioengineered artificial skin as an effective treatment option. Chronic wounds, which primarily affect the elderly population, are a significant issue in the United States.

Approximately 3% of individuals over 65 years old have open wounds, and with the projected increase in the elderly population to over 77 million by 2060, chronic wounds are expected to persist as a prevalent problem. Globally, chronic wounds are estimated to affect around 2% of the total population, indicating their adverse impact worldwide.

Secondly, North America is home to key market players, including established companies and emerging startups, contributing to the competitive landscape and driving technological advancements. These companies invest heavily in research and development to develop next-generation bioengineered artificial skin products with improved healing properties, enhanced aesthetics, and patient-specific customization.

Furthermore, the region benefits from a well-defined regulatory framework, providing a clear pathway for market entry and product approvals. Regulatory agencies, such as the U.S. Food and Drug Administration (FDA), play a vital role in ensuring the safety and efficacy of bioengineered artificial skin products, providing confidence to healthcare providers and patients.

The Bioengineered Artificial Skin Market in Europe is also Witnessing Significant Growth:

Europe has a well-established healthcare infrastructure and regulatory framework that supports the development and commercialization of advanced medical technologies. The region has witnessed increasing adoption of bioengineered artificial skin products for the treatment of chronic wounds, burns, and other skin injuries.

Several factors contribute to the growth of the bioengineered artificial skin market in Europe. Firstly, the region has a high prevalence of chronic wounds and burns, driven by factors such as an aging population, diabetes, and lifestyle-related diseases. This creates a substantial demand for advanced wound care solutions, including bioengineered artificial skin. For instance; in 2021 International Diabetes Federation (IDF), Diabetes Atlas reported 61 million cases of Diabetes in Europe, and this number is reported to increase up to 13% by 2045.

Additionally, Europe has a strong focus on research and development, fostering collaborations between academic institutions, research centers, and industry players. This emphasis on innovation has led to the development of advanced bioengineered artificial skin products with improved healing properties, such as enhanced integration with host tissues and reduced scarring.

In June 2021, Pittsburgh established itself as a global provider of artificial intelligence (AI)-based technology for wound care, Tissue Analytics, a Net Health company, announced that it had been awarded the European Union (EU) Class I(m) CE Mark. The highly sought-after designation allows the company to market and sells its mobile wound imaging and analytics solution to healthcare organizations based in EU member countries.

Key Benefits of Global Bioengineered Artificial Skin Market Report–

• Global Bioengineered Artificial Skin Market report covers in-depth historical and forecast analysis.
• Global Bioengineered Artificial Skin Market research report provides detailed information about Market Introduction, Market Summary, Global market Revenue (Revenue USD), Market Drivers, Market Restraints, Market Opportunities, Competitive Analysis, and Regional and Country Level.
• Global Bioengineered Artificial Skin Market report helps to identify opportunities in the marketplace.
• Global Bioengineered Artificial Skin Market report covers extensive analysis of emerging trends and competitive landscape.